Cardiovascular disease and type 2 diabetes | ACROSS T2D

Cardiovascular disease and type 2 diabetes

Cardiovascular disease (CVD) is the primary cause of mortality in people with T2D despite novel treatment advancements. This module explores links between CVD and T2D.

Cardiovascular disease and type 2 diabetes

Cardiovascular disease and type 2 diabetes
Cardiovascular disease and type 2 diabetes
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Cardiovascular disease and type 2 diabetes
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Diabetes greatly increases the risk of CV disease
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A large proportion of patients with T2D have CV disease
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CV disease can occur even before diagnosis of T2D
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However, most are not aware of the dangers of CV disease
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Cardiovascular disease and type 2 diabetes
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The pathophysiology of CV disease in patients with T2D is complex
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CV disease exists as a continuum
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Coronary artery disease is a prevalent comorbidity of CV disease
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Coronary artery disease is the leading cause of CV disease mortality
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Coronary artery disease is caused by atherosclerotic changes in the walls of the coronary arteries
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Coronary artery disease is often associated with other CV complications
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Patients with T2D and CAD are at higher risk of left ventricular heart failure
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Cardiovascular disease and type 2 diabetes
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CV disease occurs early and is the leading cause of mortality in patients with T2D
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Diabetes accelerates the time to first CV event
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Life expectancy is reduced by ~12 years in patients with diabetes and CV disease
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CV disease in patients with T2D is responsible for more deaths than cancer* in the general population
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CV disease is also the biggest contributor to costs related to T2D management
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Cardiovascular disease and type 2 diabetes
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T2D is a CV risk factor that determines the needfor cardioprotection
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Despite improved prognosis with advancing standard of care, patients with T2D remain at increased risk of CV mortality
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Cardioprotection is a priority consideration for patients with T2D
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Back-up slides
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CV disease can manifest as atherosclerotic events, arterial disease or heart failure
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Patients with diabetes experience worse outcomes
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CV disease is frequently asymptomatic and unrecognised
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Diabetes is associated with an increased prevalence of CV risk factors^1–3
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Life expectancy is reduced by 12 years in patients with diabetes and CV disease*
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Despite advances in therapies, life expectancy is reduced by multiple morbidities of diabetes, stroke and MI
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Diabetes* doubles the risk of vascular events
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Mortality is substantially higher in patients with T2D and chronic kidney disease
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The presence of diabetes and chronic kidney disease increases the risk of MI
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Reduced kidney function significantly increases the risk of CV events