The REWIND CVOT assessed the cardiovascular safety of dulaglutide in patients with type 2 diabetes with high CV risk, or prior CV events. This module details the results.
REWIND
REWIND
REWIND
REWIND: trial design
REWIND: key inclusion and exclusion criteria
REWIND: key inclusion criteria by age and CV disease or risk factors
REWIND: graphical representation of testing plan once primary outcome is met
REWIND: primary but not secondary outcomes were met
REWIND: baseline characteristics
REWIND: baseline CV disease and risk factors
REWIND: baseline glucose-lowering medication and CV medication
REWIND: medication used at last study visit
REWIND
REWIND: primary composite outcome of non-fatal MI, non-fatal stroke or death from CV or unknown causes
REWIND: primary composite outcome of non-fatal MI, non-fatal stroke or death from CV or unknown causes
REWIND: all-cause mortality
REWIND: CV outcomes
REWIND: primary composite outcome by baseline CV disease
REWIND
REWIND: composite microvascular outcome
REWIND: composite kidney outcome of new macroalbuminuria, sustained decline in eGFR of ≥30 ml/min/1.73 m2 or chronic RRT
REWIND: kidney outcomes
REWIND: eGFR and UACR over time
REWIND: sensitivity analyses for a sustained decline in eGFR and UACR of ≥40 and ≥50 ml/min/1.73 m2
REWIND
REWIND: HbA1c and body weight over time
REWIND: SBP and heart rate over time
REWIND
REWIND: safety summary
REWIND
REWIND: summary
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