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- ACROSS HF
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- EMPEROR-Reduced
EMPEROR-Reduced
The EMPEROR-Reduced trial evaluated the efficacy and safety of empagliflozin in patients with heart failure and a reduced ejection fraction, with or without diabetes, who were receiving standard of care treatment. This module details the design and results of the trial.
EMPEROR-Reduced
EMPEROR-Reduced
EMPEROR-Reduced
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- EMPEROR-Reduced
- EMPEROR-Reduced
- EMPEROR-Reduced
- Login or create an account to see restricted contentEMPEROR-Reduced: trial design
- Login or create an account to see restricted contentEMPEROR-Reduced: key inclusion and exclusion criteria
- Login or create an account to see restricted contentEMPEROR-Reduced: hierarchical analysis plan
- Login or create an account to see restricted contentEMPEROR-Reduced: baseline characteristics
- Login or create an account to see restricted contentEMPEROR-Reduced: baseline characteristics related to heart failure and CV disease
- Login or create an account to see restricted contentEMPEROR-Reduced: baseline characteristics related to heart failure medications and device therapy
- Login or create an account to see restricted contentEMPEROR-Reduced
- Login or create an account to see restricted contentEMPEROR-Reduced: primary composite outcome of first adjudicated CV death or HHF
- Login or create an account to see restricted contentThe effect of empagliflozin on the primary outcome was consistent across prespecified subgroups in EMPEROR-Reduced (1/2)
- Login or create an account to see restricted contentThe effect of empagliflozin on the primary outcome was consistent across prespecified subgroups in EMPEROR-Reduced (2/2)
- Login or create an account to see restricted contentEMPEROR-Reduced
- Login or create an account to see restricted contentEMPEROR-Reduced: adjudicated total HHF
- Login or create an account to see restricted contentEMPEROR-Reduced: rate of decline in the eGFR
- Login or create an account to see restricted contentEMPEROR-Reduced
- Login or create an account to see restricted contentEMPEROR-Reduced: effect on individual components of the primary outcome
- Login or create an account to see restricted contentEMPEROR-Reduced: prespecified efficacy outcomes
- Login or create an account to see restricted contentEMPEROR-Reduced
- Login or create an account to see restricted contentEMPEROR-Reduced: laboratory and other measurements
- Login or create an account to see restricted contentEMPEROR-Reduced
- Login or create an account to see restricted contentEMPEROR-Reduced: serious AEs and prespecified AEs of interest
- Login or create an account to see restricted contentEMPEROR-Reduced
- Login or create an account to see restricted contentEMPEROR-Reduced: summary